The research project aims to test if two medications – atorvastatin or metformin – may help to reduce symptoms of major depression and improve quality of life. Atorvastatin is a medication to treat high cholesterol and metformin XR is a medication to treat diabetes. There is evidence that both medications might also reduce depression symptoms.
Evidence suggests that low dose ketamine is an effective treatment for unipolar depression. Kite is a randomised controlled trial investigating whether low dose ketamine is an effective treatment for bipolar depression. Participants will be randomised to receive six doses of either ketamine or midazolam (an active control medication).
The HeLiPaD trial is testing a brief online educational program for supporting mental health in workplaces. The program was co-designed by a stakeholder group. We are recruiting workplaces to participate in a cluster randomised controlled trial to test whether the program improves help seeking and reduces stigma.
The HARMON-E trial is comparing the effects of two different group-based therapies for mental health. Participants with depression or bipolar disorder will be randomly placed into one of two groups to receive sessions from either allied health professionals, or registered psychologists.
